MedicalSutras
Pediatric Drug Dosage

Pediatric Drug Dosage

Introduction to Pedodontics

Rules that are generally used to calculate the paediatric dose of any medicine include:

  • Clark's rule (Based on the weight of the child): Weight(in lbs) / 150 x Adult Dose.

  • Young's Rule (Based on the age of the child): Age / Age + 12 x Adult Dose.

However, it is quite cumbersome to calculate the dosages each time, before writing a prescription. Hence, a ready reference guide becomes essential at every practice providing treatment to children.

Amoxicillin

  • Standard Dose: 40-50 mg/kg/day q8h (every 8 hourly).
  • Maximum Dose: 1 g/dose.
**Formulation** **Dosage** **Schedule**
Suspension (125mg/ 5ml) 2 ml/kg/day TDS (Every 8 hour)
Suspension (200mg/ 5ml) 1.25 ml/kg/day TDS (Every 8 hour)
Suspension (250mg/ 5ml) 1 ml/kg/day TDS (Every 8 hour)
Suspension (400mg/ 5ml) 0.625 ml/kg/day TDS (Every 8 hour)

Amoxicillin + Clavulanic Acid

  • Standard Dose: 30-50 mg/kg/day of amoxicillin component q8-12h.
  • Maximum Dose: 1 g/dose of amoxicillin component.
  • Suspension: 1 ml = 80 mg Amoxicillin & 11.4mg Clavulanic acid (7:1).
**Formulation** **Dosage** **Schedule**
Suspension (125mg/ 31.25 mg per 5 ml) 2 ml/kg/day TDS (Every 8 hr) or BD (Every 12 hr)
Suspension (200mg/ 28.5 mg per 5 ml) 1.25 ml/kg/day TDS (Every 8 hr) or BD (Every 12 hr)
Suspension (250mg/ 62.5 mg per 5 ml) 1 ml/kg/day TDS (Every 8 hr) or BD (Every 12 hr)
Suspension (400mg/ 57 mg per 5 ml) 0.625 ml/kg/day TDS (Every 8 hr) or BD (Every 12 hr)
Tablet : 625 mg (500/125 mg) (4:1) 30-50 mg/kg/day TDS (Every 8 hr) or BD (Every 12 hr)
Tablet : 1000 mg (875/125 mg) (7:1) 30-50 mg/kg/day TDS (Every 8 hr) or BD (Every 12 hr)

Metronidazole

  • Standard Dose (Anaerobic Infections): 20-30 mg/kg/day q6h.
  • Maximum Dose: 1 g/day.
**Formulation** **Dosage** **Schedule**
Suspension (125mg/ 5 ml) 1.2 ml/kg/day Every 8-12 hr
Suspension (200mg/ 5 ml) 0.75 ml/kg/day Every 8-12 hr
Tablet (250 mg) 20 - 30 mg/kg/day Every 8-12 hr
Tablet (400 mg) 20 - 30 mg/kg/day Every 8-12 hr

Paracetamol

  • Standard Dose: 5-10 mg/kg q6-8h.
  • Maximum Dose: 40 Mg/kg/24hr.
**Formulation** **Dosage** **Schedule**
Suspension (120mg/ 5ml) 0.5 ml/kg (=12 mg/kg) Every 6 hr
Suspension (250mg/ 5ml) 0.2 ml/kg (=10 mg/kg) Every 6 hr

Ibuprofen

  • Standard Dose: 5-10 mg/kg q6-8h.
  • Maximum Dose: 40 mg/kg/24hr.
Formulation Dosage Schedule
Suspension (100mg/5ml) 0.5 ml/kg Every 6 hr